|
Country: Spain
City: Valencia
IHTC:
Hospital Universitario La Fe
Unidad de Hemostasia y Trombosis
Avda. de Campanar,
21 46009 - Valencia
Tel.: 34 96 197 3052
Fax: 34 96 1973052
Email: aznar_jan@gva.es
Website: http://www.dep7.san.gva.es/
Director: José A. Aznar
Responsible for training: José A. Aznar
Fellowship logistics coordinator: José A. Aznar
Year of IHTC designation: 1997
Areas of specialty: General hemophilia care; physiotherapy; pediatrics; laboratory diagnosis (not genetics); genetic diagnosis. Physical therapist
DESCRIPTION OF TRAINING PROGRAM
Clinical activities: Comprehensive hemophilia care (simultaneous hematologic and musculoskeletal care); epidemiologic inhibitor study and immune tolerance treatment in haemophilia A; primary prophylaxis; synoviorthesis; joint evaluation (clinical-radiological criteria); comprehensive care in von Willebrand disease; comprehensive care other coagulopathies. The staff is composed of three hematologists, a physician specialized in joint care and hemophilic arthropathy (physical therapist), two geneticists, two biologists, three nurses and 3 auxiliary nurses, and an office worker.
Patients comprise 1,659 patients classified as follows: 286 hemophilia A, 26 hemophilia B, 302 von Willebrand disease, 494 suffering from other coagulopathies; 111 affected by some thrombopathy, and 440 hemophilia carriers (413 hemophilia A and 27 hemophilia B).
In addition, we have performed genetic diagnosis in 194 unrelated families affected by hemophilia, and in 73 families affected by von Willebrand disease.
Laboratory activities/research: General laboratory diagnose of most coagulopathies (use of clotting, chromogenic and antigenic methods). Laboratory diagnose of von Willebrand disease (ristocetin cofactor, RIPA, collagen binding assay, FVIII binding assay, antigen of VWF, multimeric pattern). Inhibitor screening and titration (Kasper test, Bethesda and Nijmegen assays). Western blot of FVIII for epitope mapping of anti-FVIII antibodies (specificity against light or heavy chain of FVIII). Direct/indirect genetic diagnose for hemophilia A, B and von Willebrand disease.
Multidisciplinary activities/research: Training program treatment for fathers; training program on self-treatment for patients; program on strength improvement and care of musculoskeletal system; sport and hemophilia program; special program for swimming in hemophilia.
Additional information: Twinning with Panamá (WFH Award in 2002). In this context, the following hemophilia pediatric specialists (Hospital del Niño) have visited our Congenital Coagulopathy Unit: a laboratory technician, nurse, physician specialized in joint care and hemophilic artropathy (physical therapist), physician specialized in radiology, and two hematologists. Other fellows who have visited our centre include h ematologists from El Salvador, Chile, Uruguay, Panamá, and Cuba ; a physiotherapist from Venezuela; an orthopedic surgeon from the Dominican Republic; geneticist from Chilel and laboratory technican from Panamá. The centre can train up to three fellows annually. There are two training periods: from January to June, and from October to December. Any of these periods would be fine for us to receive the candidates.
DESCRIPTION OF IHTC FACILITIES
Location: La Fe University Hospital (Congenital Coagulopathy Unit), in Valencia - Spain
Climate: Typically Mediterranean. Very few rainy days, occurring mainly in autumn, the winter is mild (temperature is never below 0ºC), Autumn and spring are warm and summer is very hot, with both high temperatures and humidity levels (35-40º C degrees and 50-80% humidity)
Accommodation (residence, meals, etc...): There is a residence for university students and teachers located in the centre of the city, 25 minutes from the hospital. The residence also offers full board.
Transportation: Bus connecting the residence and the hospital. Subway is also available.
Language: Spanish
Financial assistance: Dependent on WFH funds.
Cost of living (per week): 450 USD
Communications tools for trainees: Internet, telephone and computers available at the Hospital and the Residence
Other local support provided for trainees: In the residence there is a library, room for cultural events, and sports gym.
RELEVANT PUBLICATIONS BY IHTC STAFF
Casaña P, Cabrera N, Haya S, Cid AR, Aznar JA. Von Willebrand's disease: a novel mutation, P1824H and the incidence of R1205H defect among families with dominant quantitative von Willebrand factor deficiency. Haematologica 2006; 91(8):1130-1133.
Martínez J,Cid AR, de la Rubia J, Gimeno R. Aznar JA. Treatment of intra-abdominal bleeding with recombinant activated factor VII in a patient with disseminated intravascular coagulation secondary to septic shock.Blood Coagulation and Fibrinolysis 16: 297-299, 2005.
Espinós C, Casaña P, Haya S, Cid AR, Aznar JA.Molecular Analyses in hemophilia B families: identification of six new mutations in factor IX gene. Haematologica 88: 235-236, 2003.
|
