Severity of hemophilia
The severity describes how serious a problem is. The level of severity depends on the amount of clotting factor that is missing from a person’s blood.
|Level||Percentage of normal factor activity in blood||Number of international units (IU) per millilitre (ml) of whole blood|
|| 0.50–1.5 IU
|| 0.05–0.40 IU
|| 0.01–0.05 IU
|| less than 1%
|| less than 0.01 IU
People with severe hemophilia usually bleed frequently into their muscles or joints. They may bleed one to two times per week. Bleeding is often spontaneous, which means it happens for no obvious reason.
People with moderate hemophilia bleed less frequently, about once a month. They may bleed for a long time after surgery, a bad injury, or dental work. A person with moderate hemophilia will rarely experience spontaneous bleeding.
People with mild hemophilia usually bleed as a result of surgery or major injury. They do not bleed often and, in fact, some may never have a bleeding problem.
Updated May 2012