United States

Country: USA
City: Chapel Hill, North Carolina

IHTC: University of North Carolina Hemophilia & Thrombosis Center
120 Mason Farm Road, CB 7035
1042 Genetic Medicine Building
Chapel Hill, NC  27599-7035
Tel.: 919-966-4736
Fax: 919 962 8224

Director: Dr. Nigel S. Key
Responsible for training: Dr. Alice Ma, Dr. Micah Mooberry, Dr. Tyler Buckner, Dr. Paul Monahan, Dr. Brent Weston

Fellowship logistics coordinator: Christine Hill (
Year of IHTC designation: 1972

Areas of specialty: Adult and pediatric hematology; Laboratory diagnosis; Nursing; Physiotherapy/ Occupational therapy; Psychology/ Social services


Location: In the Central Piedmont region of North Carolina, Chapel Hill is a town of approximately 45,000 people, most of whom are affiliated with the university. It is neighbored by Durham, home of Duke University, Raleigh, the state’s capital, and the Research Triangle Park, a planned research park that is home to approximately 100 research and development facilities.

Climate: Rather temperate, with winter temperatures which are rarely below 25°F. However, the summers are hot and humid with temperature highs hovering around 90°F in July and August.

Accommodation: There are many rental accommodations available in the area, as well as accommodations with graduate students.

Language: English


Clinical activities: As the second largest HTC in the United States, the University of North Carolina Comprehensive Hemophilia Diagnostic and Treatment Center (UNC) has a wealth of clinical material. We provide annual care for more than 640 patients with hemophilia, von Willebrand disease and other bleeding disorders. Our staff is comprised of six physicians, three nurses, two physical therapists, and one genetic counselor. The centre participates in numerous clinical trials for the development of new products for the treatment of hemostatic disorders, as well as for the treatment of HIV and hepatitis C infection.

The University of North Carolina also has a strong program in thrombosis diagnosis and treatment. More than 500 patients with various thrombosis-related conditions and complications are seen yearly and the program provides excellent training in genetic diagnosis, vascular interventional radiology and Doppler ultrasound techniques.

Laboratory activities/research: The John B. Graham Clinical Coagulation Laboratory as well as the UNC Hospitals Core Laboratory provides onsite testing for patients followed by our centre. There are six to seven personnel in the lab. Researchers are working in a variety of areas, including the structure, function, and initiation of coagulation; inhibitors to coagulation; platelet physiology and function and gene therapy for hemophilia.

Multidisciplinary activities/research: The center has a multidisciplinary team (physician, nurse, social worker, physical therapist, and genetic counselor) dedicated to the care of individuals/families affected by bleeding disorders. The entire team is present during pediatric and adult clinics to assure that health and psychosocial needs are addressed and continuity of care is provided. The center also works collaboratively with Federal, State, and community partners to promote comprehensive care and to improve quality of life across the lifespan by providing direct patient care, education, and research. Partners include: Center for Disease Control and Prevention; National Hemophilia Program Coordinating Center, American Thrombosis and Hemostasis Network (ATHN); My Life Our Future; US Department of Health and Human Resources; The Hemophilia Alliance Foundation; and the National Hemophilia Foundation (NHF).

To see a sample curriculum of the training that will be provided, please click on the following links:

Sample schedule (general comprehensive care): PDF
Laboratory Diagnosis: PDF 

For more information on the centre, please click here.

Updated May 2015