United States

Country: USA
City: Rochester, Minnesota

Mayo (Rochester) Comprehensive Hemophilia Center, and International Hemophilia Training Center (WFH) 
Mayo Clinic/Foundation and Mayo Medical School
200 First St. SW
Rochester, MN 55905 USA
Tel.: 507 284 8634
Fax: 507 538 6803

Director: 1) Rajiv K. Pruthi, M.D. (CHC and IHTC Director, Director, Mayo Special Coagulation Laboratory and Coagulation Programs), 2) Vilmarie Rodriguez, M.D. (Director, Pediatric Hemophilia Program), 3) Aneel A Ashrani (Co-director for coagulation education) 4) William L. Nichols, MD (former IHTC Director 1990-2008)
Medical Associates: (Hematologists): Rajiv K. Pruthi, M.D., William L. Nichols, M.D, Vilmarie Rodriquez, M.D., John A. Heit, M.D., Aneel A. Ashrani, MD, C. Christopher Hook, M.D., Dennis A. Gastineau, M.D., Animesh Pardanani, M.D., Mrinal Patnaik, M.D., (Education Specialists): Laynalee K. Cardel, M.T. (ASCP), Elizabeth Kock, M.T. (ASCP), (Hemophilia center RNs): Amy L. Eckerman, R.N., Aubrey Manahan, R.N., Dawn Olive, R.N. and (Hemophilia Center Social Worker): Melinda Otto, M.S., L.I.C.S.W
Fellowship logistics coordinator: Drs. Rajiv K Pruthi and Aneel A Ashrani (
Year of IHTC designation: 1974

Areas of specialty: Adult and pediatric hematology; Laboratory diagnosis and hemostasis; Nursing; Orthopedic care and surgery; Blood Banking; Molecular genetics; Psychology/ Social services


Location: Rochester, Minnesota (north central U.S.)

Climate: Continental – pleasant summers and cold winters

Accommodation: Available in Mayo-affiliated facilities at subsidized rates

Language: English, Spanish, French and Russian.


Clinical activities: The strengths of the Mayo (Rochester) IHTC and its programs mainly reflect:

  1. Truly comprehensive availability at Mayo Medical Center of compassionate expertise in all recognized medical, surgical, dental and laboratory specialty services for patients of all ages;
  2. Experience of managing a broad range of pathology conditions as encountered in a very large referral center;
  3. Collaborative nature of Mayo’s academic medical practice, education and research; and
  4. Integrated interactions of Mayo’s coagulation diagnostic and research laboratories, and coagulation clinical centers including the Coagulation Clinic, Comprehensive Hemophilia Center and Thrombophilia Center. 

Mayo’s Hemophilia Center annually provides comprehensive evaluations and care for more than 300 patients with hereditary bleeding disorders, in addition to assisting in the management of an additional 100 such patients encountered annually for initial or sporadic visits. The patients are mainly of regional residence, but also include many of distant and international origins.

The coagulation consulting staff includes eight hematologists, thirty-five laboratory personnel, three nurses, a social worker, and a data manager. Mayo’s Medical Genetics Department assists in evaluating individuals and families with hereditary hemostatic disorders. Laboratories within the Special Coagulation Laboratories or in the Division of Laboratory Genetics provide DNA diagnostic testing for hereditary bleeding disorders such as hemophilia A and B, and certain variants of von Willebrand disease, as well as hereditary thrombophilia.

Outpatient coagulation clinic consultations and evaluations are provided for more than 500 patients annually with bleeding or thrombotic problems, with a larger number of hemostasis-related consultations provided in the outpatient Thrombophilia and Vascular Centers, and in the Mayo hospitals. Mayo also has been designated since 1990 as a Thrombosis and Vascular Training Center (TVTC) by the International Society for Thrombosis and Haemostasis (ISTH), such that trainees can also be better exposed to thrombosis and anticoagulation teaching when indicated.

Laboratory activities/research: Mayo’s Coagulation Laboratories are directed by Dr. J.A. Heit, supervised by Ms. B.L. Meyers, and staffed by more than 35 laboratory technologists, aides and secretaries. In addition to Mayo’s internal practice, the laboratory has a very large national and international referral practice via Mayo Medical Laboratories.

Mayo’s Comprehensive Hemophilia Center (CHC) is one of five national hemophilia centres in the U.S. participating in a CDC-sponsored study of outcomes associated with comprehensive models of care for women with bleeding disorders and menorrhagia.

To see a sample rotation schedule for a Laboratory science training, please click here.

Updated July 2014